“Transcure ranks as a leading medical billing company in South Carolina, delivering advanced RCM, denial management, and accurate coding support. Other top providers, including Medical Revenue Solutions LLC, Medical Billing Center, EZ RCM Billing Services, and Apple Billing, help practices streamline claims, improve cash flow, reduce administrative burden, and boost revenue.”
South Carolina’s healthcare landscape includes hospitals, clinics, and private practices serving patients across both urban and rural areas. Despite this, many providers struggle with complex billing requirements, delayed reimbursements, and administrative backlogs that strain cash flow.
According to Healthcare Finance News, insurers initially denied about 11.8% of submitted medical claims in 2024, up from prior years, adding pressure on practices’ revenue cycles.
To manage these challenges, more South Carolina healthcare providers are turning to experienced medical billing companies that help improve revenue flow. This article highlights the top 10 medical billing companies in South Carolina to help ensure consistent cash flow.
- Transcure
- Medical Revenue Solutions LLC
- Medical Billing Center (MBC)
- EZ RCM Billing Services, LLC
- Apple Billing
- Health Information Associates (HIA)
- Lowcountry Billing Services, LLC
- EZ MD Solutions
- The EMS Billing & Coding Services Of The Carolinas LLC
- Physician Services USA
1. Transcure
Transcure is a leading medical billing company that handles every step of the revenue cycle to help practices get paid faster with fewer errors. With over 23 years of experience. We provide complementary audit services for practices of all sizes.
Furthermore, our AI agent CLAIR handles claim scrubbing, and DEXA manages denial analysis and appeals. Also, ARIS handles AR follow-ups, and REMITA manages payment posting and reconciliation, along with over 1,100 certified billers and coders to reduce manual work and maximize clean claim submissions.
Practices that adopt Transcure’s AI agents see revenue growth of 10–15%, cleaner, more accurate claims, and real-time financial visibility that helps leadership make smarter decisions.
| Best For | Automated RCM services for high accuracy |
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| Founded in | 2003 |
2. Medical Revenue Solutions LLC
Medical Revenue Solutions LLC is a top Medical billing company based in South Carolina that specializes in comprehensive revenue cycle management. They offer iClaim “no-headache” billing, which gives practices control over patient records.
Moreover, they offer EMRx tailored billing solutions and QuickCollect/ChoicePay tools to improve patient collections. Their AuditGuard service reviews coding, billing, and reimbursements to uncover revenue opportunities. While their VirtualCare and other tools help streamline operations and optimize cash flow.
| Best For | Best for personalized patient billing engagement and compliance‑driven revenue cycle support. |
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| Founded in | 2011 |
3. Medical Billing Center (MBC)
Medical Billing Center is a top Medical billing agency in South Carolina, specializing in outpatient therapy revenue cycle management with over 20 years of experience. Founded by physical therapy professionals, MBC focuses on billing and collections for physical, occupational, and speech therapy practices.
Moreover, the company integrates with various EMRs, ensuring claims are filed promptly. Additionally, detailed analytics to improve cash flow and compliance, enabling clinics to focus on patient care while optimizing reimbursement and reducing denials.
| Best For | Specialized outpatient therapy billing with fast claim turnaround and custom EMR integration |
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| Founded in | 2001 |
4. EZ RCM Billing Services, LLC
EZ RCM Billing Services is a top Medical billing firm in South Carolina that delivers cost-efficient revenue cycle solutions nationwide. Specializing in accurate claims processing and reimbursement, they manage key billing functions, including AR and denial management.
Furthermore, their firm’s team supports provider credentialing, referral/utilization review, and patient billing, while adapting to multiple EMR systems. Their focus on tailored billing support helps practices improve cash flow and reduce administrative burden.
| Best For | Responsive, cost-efficient billing support with rapid turnaround and broad EMR adaptability |
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| Founded in | 2018 |
5. Apple Billing
Apple Billing is a top Medical billing provider in South Carolina, based in Okatie, that focuses on maximizing reimbursements and improving revenue cycle performance. They handle accurate medical billing services for small to medium‑sized medical practices.
The company tailors workflows to each client’s needs and submits claims promptly and accurately, ensuring practices receive payments quickly and consistently. Apple Billing combines hands‑on services with proactive tracking to help practices maintain a steady revenue stream and reduce administrative strain.
| Best For | Personalized, practice‑specific billing workflows that boost reimbursements for small to medium medical practices |
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| Founded in | 1992 |
6. Health Information Associates (HIA)
Health Information Associates is a leading medical billing outsourcing company in South Carolina, known for its deep expertise in medical coding and compliance. Rather than traditional billing, HIA focuses on accurate coding support, comprehensive audit services, and documentation improvement to reduce compliance risk.
Additionally, their remote coding teams, advanced audit platforms, and education programs support hospitals, ASC facilities, physician groups, and other care settings nationwide.
| Best For | Expert coding compliance and comprehensive audit support that enhances reimbursement accuracy and reduces risk. |
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| Founded in | 1992 |
7. Lowcountry Billing Services, LLC
Lowcountry Billing Services is a family-owned, relationship-driven EMS billing company serving agencies across South Carolina. With over 30 years of expertise, they streamline revenue cycles, reduce claim denials, and ensure regulatory compliance for EMS, municipalities, and private providers.
Additionally, their personalized approach emphasizes a human-first billing approach and timely claims processing. Also, they offer detailed reporting, enabling agencies to focus on patient care while maintaining financial integrity and operational efficiency.
| Best For | EMS billing, municipal, and private ambulance billing |
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| Founded in | 1990 |
8. EZ MD Solutions
EZ MD Solutions is a top Medical billing company based in South Carolina, providing comprehensive RCM and practice growth solutions. Their expert team ensures accurate billing, timely claims processing, and denial management, while also providing virtual medical assistance, transcription, and credentialing.
Moreover, by integrating digital marketing with HIPAA-compliant processes, they enhance the patient experience and clinic efficiency. By helping healthcare providers reduce costs, increase collections, and focus on quality care without administrative burdens.
| Best For | Streamlining medical billing and practice management with precision and care. |
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| Founded in | 2015 |
9. The EMS Billing & Coding Services Of The Carolinas LLC
The EMS Billing & Coding Services Of The Carolinas is the best medical billing company in South Carolina, offering RCM services to healthcare providers. Their certified team of billers and insurance specialists ensures accurate claim submission, efficient denial handling, and timely payments.
Furthermore, their certified billing specialists and insurance experts ensure precise and confidential claim processing. Additionally, they serve practices nationwide by reducing administrative burdens and improving cash flow, while maintaining strict compliance and confidentiality standards.
| Best For | Personalized attention for each healthcare provider, prioritizing operational efficiency |
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| Founded in | N/A |
10. Physician Services USA
Physician Services USA is a South Carolina-based medical practice management firm with over 23 years of experience. They specialize in streamlining medical billing, revenue cycle management, and practice operations, enabling healthcare providers to focus on patient care.
Moreover, their expert team serves a range of specialties, including private practices, FQHCs, RHCs, and laboratories, ensuring accurate coding. Additionally, their efficient claim submission and effective collections optimize reimbursement and minimize revenue loss.
| Best For | Best for expert medical billing paired with tailored practice growth and revenue management. |
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| Founded in | 2002 |
How Our Editors Selected the Top Medical Billing Companies in South Carolina
Our editors evaluated each firm’s local visibility, credibility, and search performance in South Carolina. We reviewed online feedback and testimonials to judge service quality and client satisfaction. Key factors like billing expertise, reliability, technology use, and reputation were compared. Only those providers demonstrating strong performance in revenue cycle management and client outcomes were included in the final list of top medical billing companies.
What are the best medical billing providers in the USA?
Transcure is widely recognized as one of the best medical billing providers in the USA, frequently ranking first due to its comprehensive revenue cycle management and high clean claim rates. Other leading billing firms include CBS Medical Billing, Med USA, Provider Care Billing, and Practolytics, all of which provide end‑to‑end RCM services, including claims processing, denial management, and credentialing, to help practices boost collections and maintain steady cash flow nationwide.
What are the benefits of outsourcing medical billing in South Carolina?
Outsourcing medical billing in South Carolina helps practices reduce errors and lower denial rates by leveraging expert billing and coding teams familiar with current payer rules and compliance standards. This approach accelerates reimbursements, improves cash flow, and reduces costs associated with in‑house staff, software, and training. Practices also gain access to advanced billing technology, detailed financial reporting, and more time to focus on patient care instead of administrative tasks.
What percentage do medical billers take in South Carolina?
Medical billing companies in South Carolina generally charge about 6%–10% of monthly collections, depending on the scope of services and practice size. Some firms also offer flat per-claim pricing or hybrid models based on volume and specialty. Compared to this range, Transcure typically charges around 5% for end-to-end RCM, credentialing, audits, and compliance support, providing practices with predictable costs while improving overall revenue performance.
What are the five best medical billing companies in South Carolina?
The five best medical billing companies in South Carolina are as follows:
- Transcure
- Medical Revenue Solutions LLC
- Medical Billing Center (MBC)
- EZ RCM Billing Services, LLC
- Apple Billing
Which is the best medical billing company in South Carolina?
Transcure is widely recognized as one of the best medical billing companies in South Carolina and across the USA, known for its robust RCM platform that delivers accurate claim processing, proactive denial management, and fast reimbursements. With over 1,100 certified billers and coders supporting 40+ specialties and integrating with 30+ EHR systems, Transcure helps practices consistently reduce AR days, improve clean-claim rates, and increase revenue performance.
