“The best medical billing companies in Irvine, California, include Transcure, which offers AI‑enhanced billing agents to handle key tasks such as claim scrubbing, coding accuracy, and A/R follow‑up. Other leading billing companies in Irvine include ALTOS, Certified Healthcare Billing, and Claim n Billing, which help providers improve revenue collection and manage their billing processes efficiently.”
Irvine, California, has a strong healthcare system where medical billing plays an important role. Practices deal with high claim volumes, changing regulations, and payer rules that affect revenue. Across the U.S., including Irvine, about 20% of both in-network and out-of-network claims are denied due to errors and documentation issues.
Professional billing support helps practices manage changing payer rules, coding needs, and unpaid claims, leading to faster payments and more accurate revenue management. This list gives an overview of the top medical billing companies in Irvine, California, to help you choose the right billing provider for your practice.
- Transcure
- Altos
- Certified Healthcare Billing
- Claim N Billing
- 24/7 Medical Billing
- Cosentus
- 24/7 Billing Paradise
- Physicians Management Network Inc.
- The Medcor Group Inc
- Indigo Billing LLC

Table of Contents
Toggle1. Transcure

Transcure is a medical billing company in Irvine, California, offering end-to-end medical billing and RCM services for over 40 specialties. Our company handles more than 2.7 million claims and has processed over $500 million in claims, which shows our experience and reliability.
We improve RCM with seven dedicated AI agents that handle routine tasks like insurance eligibility checks (ELIXA) and accurate coding (CODIN). By using this technology, many clients see improved financial performance, with some reporting up to 20% revenue growth within months.
Moreover, we seamlessly integrate with over 40 EHR systems, including eClinicalWorks, Athenahealth, and CareCloud, to ensure smooth billing. Also company provides daily, weekly, and monthly performance reports and offers 24/7 support for claims.
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| Founded In | 2002 |
2. ALTOS

ALTOS is a billing company based in Irvine, California, with over 20 years of experience in healthcare services. The company serves 15+ medical specialties, including Orthopedics, Chiropractic, and Nephrology, which demonstrates its broad expertise.
Additionally, the company has a certified coding team and expertise in handling insurance claims, which helps practices to improve collections and lower denials. They follow HIPAA rules, which ensure patient data stays secure and protect the practice from legal risks.
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| Founded In | 2002 |
3. Certified Healthcare Billing

Certified Healthcare Billing is a company based in Irvine, California, offering pricing starting at 2.5% with no binding contracts. Moreover, the company supports both inpatient and outpatient hospital billing, which makes it a reliable choice for providers.
The company submits 100% of claims within 24 hours, helping providers get paid faster and avoid payment delays. Also company maintains a 99% clean claim rate and employs over 50+ professional billers and coders to ensure accurate coding.
| Best For | Small Clinics to Complex Hospital Systems |
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| Founded In | 2011 |
4. Claim N Billing

Claim N Billing is a medical billing company in Irvine that supports small- to mid-sized healthcare providers with accurate billing. Furthermore, the company provides Doula Billing Services that handle Medi-Cal claims, denials, and follow-ups.
Additionally, the company is approved by insurance providers such as Hoag, CalOptima, and Blue Cross, which allows them to handle claims smoothly. The company also provides transparent reporting to practices, which support long-term revenue growth.
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| Founded In | 2024 |
5. 24/7 Medical Billing

24/7 Medical Billing is a trusted medical billing firm in Irvine that provides end-to-end medical billing services. The company helps practices increase their revenue by up to 30%, which improves financial performance.
Additionally, the company helps providers reduce operational costs by around 50%, which improves the overall efficiency of practices. Moreover, their team of experienced coders familiar with the complexities of ICD, CPT, and HCPCS helps practices improve billing accuracy.
| Best For | 30+ medical specialties, including Mental Health, Neurology, and Oncology. |
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| Founded In | 2005 |
6. Cosentus

Cosentus is a well-known billing company in Irvine, California, specializing in Practice Management and Revenue Cycle Management, with decades of experience. Additionally, the company uses advanced AI and practice management platforms to increase reimbursements.
They offer API integrations with existing healthcare systems, ensuring seamless workflow. The company also helps providers increase revenue by up to 30% through accurate billing and faster reimbursements.
| Best For | A multi-specialty billing company, including
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| Founded In | 1999 |
7. 24/7 Billing Paradise

24/7 Billing Paradise has over 20 years of experience in healthcare RCM and is based in Irvine, California. Moreover, the company serves diverse specialties such as Behavioral Health, OB/GYN, and Neurology.
Additionally, the company achieves a 98% first-pass claim acceptance rate, making it a reliable choice for providers. The company maintains full compliance with HIPAA, SSAE16 SOC2, and VAPT audits, ensuring strict data security protocols are in place.
| Best For | Group practices and physician groups |
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| Founded In | 2004 |
8. Physicians Management Network Inc.

Physicians Management Network Inc. has over 20 years of experience in healthcare revenue cycle management, and it is based in Irvine, California. Moreover, they are dedicated to delivering billing services to multiple specialties, including Cardiology and Gastroenterology.
The company has helped healthcare practices collect over $150 million in revenue and streamline the billing process. In addition, it helps keep accounts receivable (A/R) under 90 days and maintains low claim denial rates.
| Best For | Internal and Family Medicine |
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| Founded In | 2000 |
9. The Medcor Group Inc

The Medcor Group Inc. is a billing company based in Irvine, California, with over 20 years of experience in FQHC, CHC, and rural health billing. On average, partnering with Medcor Group Inc. helps practices increase their revenue by up to 12%.
The company covers multiple specialties, including Internal Medicine and Behavioral Health, which helps practices in billing. Their services integrate with 9 EHR software, including eClinicalWorks, making it easy for practices to continue with their existing setup.
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| Founded In | 1998 |
10. Indigo Billing LLC

Indigo Billing LLC is a medical billing company in Irvine that provides HIPAA-compliant, end-to-end RCM services. Additionally, the company supports over 250 facilities and is trusted by hundreds of mental and behavioral health providers.
In addition, they provide transparent financial reporting and maintain a 98% client retention rate. Their experienced billing and coding team manages services like utilization review and denial management.
| Best For | Large & Small Behavioral Health Organizations |
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| Founded In | 2021 |
How Our Editors Selected the Top Medical Billing Companies in Irvine?
Our editors selected the top medical billing companies in Irvine, CA, using a thorough review process focused on effectiveness. We looked at companies that frequently appear on reputable platforms like Yelp, TrustPilot, GoodFirms, and industry directories.
We also carefully reviewed their websites and evaluated them on key factors, including billing accuracy, range of specialties, and expertise. In addition, we considered compliance with HIPAA and other regulations, EHR integration, transparent pricing, and responsive customer support.
What are the Best Medical Billing Companies in California?
Transcure is one of the top medical billing companies in California, along with California Medical Billing, My RCM Group, CareCloud, and MedKarma. All of these companies offer comprehensive billing and revenue cycle management services to help healthcare practices maximize reimbursements and streamline operations.
What are the Benefits of Outsourcing Medical Billing in Irvine, CA?
Outsourcing medical billing in Irvine, CA, helps practices reduce costs by 30–40% by eliminating the need for an in-house billing team. Skilled billing teams handle complex claims, increase accuracy, and speed up reimbursements. Professional billing companies also follow HIPAA standards and provide advanced reporting to enhance revenue cycle visibility.
What Percentage Do Medical Billers take in Irvine, CA?
Medical billing companies in Irvine, CA usually charge a percentage of the revenue they collect, typically 3–8% of monthly collections or $3–$10 per claim. Smaller practices may spend around $40K annually, while larger ones can exceed $1M.
Which is the Best Medical Billing Company in Irvine, CA?
Transcure is a leading medical billing company in Irvine, CA, serving nearby states. With AI-powered billing and revenue management services, the company combines technology with certified coders to help practices achieve 99.99% clean claim accuracy and a 1% denial rate.
What are the Five Best Medical Billing Companies in Irvine, CA?
The five leading medical billing companies in Irvine, CA are Transcure, ALTOS, Certified Healthcare Billing, Claim N Billing, and 24/7 Medical Billing. Each of these companies offers healthcare providers accurate billing, revenue cycle management, and claims support.
What Factors Should I Consider Before Hiring a Medical Billing Company in Irvine, CA?
Before hiring a medical billing company in Irvine, CA, consider their experience with your specialty, accuracy, and clean claim rates. Also, check HIPAA compliance, EHR integration, reporting transparency, pricing, turnaround times, denial management, and client reviews to ensure they can boost your practice’s revenue.



