“The top medical billing companies in Knoxville, TN include Transcure, Cvikota Medical Business Services, and Direct Medical Management Services Inc. Many serve local practices, while others provide remote billing services nationwide for greater flexibility and efficiency.”
Knoxville, Tennessee, is a vibrant healthcare center with over 25 hospitals and hundreds of outpatient clinics serving the region. Studies show that medical practices in the U.S. lose up to 20–30% of potential revenue due to billing errors and claim denials, highlighting the critical need for efficient billing solutions.
With the growing complexity of Medicare, Medicaid, and private insurance claims, many Knoxville practices face challenges in managing revenue cycles effectively. Outsourcing to specialized medical billing companies helps practices reduce denials, improve cash flow, and focus more on patient care. Below are the top medical billing companies in Knoxville, TN that healthcare providers can trust.
- Transcure
- Cvikota Medical Business Services
- Direct Medical Management Services Inc
- Valley View Medical Billing
- Medisys Data Solutions Inc
- PrimeCare Medical Billing Services, LLC
- 24/7 Medical Billing Services
- Providers Care Billing
- MedsIT Nexus
- Resilient Medical Billing Service LLC

Table of Contents
Toggle- 1. Transcure
- 2. Cvikota Medical Business Services
- 3. Direct Medical Management Services Inc
- 4. Valley View Medical Billing
- 5. Medisys Data Solutions Inc
- 6. PrimeCare Medical Billing Services, LLC
- 7. 24/7 Medical Billing Services
- 8. Providers Care Billing
- 9. MedsIT Nexus
- 10. Resilient Medical Billing Service LLC
- How Our Editors Selected the Top Medical Billing Companies in Knoxville, TN?
- What are the best medical billing companies in Tennessee?
1. Transcure

With its nationwide reach and local expertise, Transcure leads the list of the top medical billing companies in Knoxville. We use dedicated AI agents to automate the stages of medical billing, from eligibility verification to coding and payment collection. The advanced automation helps maintain a 99.99% first-pass clean claim rate and a nearly 1% claim denial rate.
Along with automation, our expert AAPC-certified billers and coders support billing for 40+ specialties, including Family Practice, Dentistry, and Cardiology. We help healthcare practices reduce A/R days to below 24 while achieving up to a 30% reduction in overall accounts receivable.
Our team is trained in 40+ EHR software, including athenahealth and AdvancedMD, so you can continue using the software you already have. Plus, we are well-versed in Tennessee medical billing laws, including timely filing limits, balance billing regulations, and payer-specific Medicaid and Medicare guidelines.
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| Experience | 23 years |
2. Cvikota Medical Business Services

Cvikota Medical Business Services (MBS), now part of Kovo RCM, has over 50 years of experience providing comprehensive medical billing and revenue cycle management services. Serving independent physicians, hospitals, and office-based practices across the U.S., the company offers personalized billing services to maximize reimbursements.
Their team of seasoned RCM specialists and AI-driven workflows helps practices streamline eligibility verification, claims submission, coding, and accounts receivable management. They offer percentage-based pricing and data-driven insights through a secure client portal.
| Best For | Independent physicians, hospitals, office-based practices, behavioral health clinics, and small-to-medium healthcare providers seeking personalized medical billing and RCM services. |
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| Experience | Over 50 years |
3. Direct Medical Management Services Inc

Direct Medical Management Services was established with the mission to provide affordable and quality medical billing services to all its clients. Their team comprises highly trained medical billing professionals with 30 years of combined billing experience.
Additionally, they manage chart reviews and risk assessments on a practice’s behalf. Moreover, the company has trained its team to promptly resolve unpaid claims. They also offer credentialing solutions to ensure you are in the right network.
| Best For | Small to medium healthcare practices seeking full-service and affordable billing services. |
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| Experience | 30+ years |
4. Valley View Medical Billing

Valley View Medical Billing is a Medical billing provider Knoxville, TN, offering compliant claim submissions and thorough accounts receivable follow‑up. They focus on reducing billing complexity and administrative costs while ensuring regulatory compliance and responsive support.
Their services include denial management, electronic claim submission, payment posting, and credentialing support. The company also ensures ongoing monitoring of unpaid claims to improve collections and practice revenue.
| Best For | Small to medium medical practices seeking compliant billing with faster payment turnaround and full accounts receivable management. |
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| Experience | 9 years |
5. Medisys Data Solutions Inc

Medisys Data Solutions, based in Knoxville, TN, is a specialized medical billing company offering HIPAA-compliant services. Their team of certified coders ensures precise CPT and ICD-10 coding for accurate, compliant documentation.
Providers receive dedicated account managers, 24/7 support, and a complimentary practice analysis. The company can integrate with existing billing software and provide continuous follow-up on unpaid or denied claims, helping practices optimize revenue and improve collections.
| Best For | Multi-specialty healthcare providers |
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| Experience | 15 years |
6. PrimeCare Medical Billing Services, LLC

PrimeCare Medical Billing Services is a leading medical billing company in Knoxville, offering comprehensive support from claim submission to accounts receivable follow-up. The company specializes in credentialing and denial management, catering to more than 40 medical specialties.
With cost-effective pricing plans designed to meet the needs of practices of all sizes, PrimeCare ensures high-quality service while maintaining a proven track record of consistently high clean claim rates for its partner practices.
| Best For | Healthcare providers seeking end-to-end billing solutions across multiple specialties |
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| Experience | 12 years |
7. 24/7 Medical Billing Services

24/7 Medical Billing Services is a top medical billing company in Knoxville, providing around-the-clock physician billing support. With over 500 employees and a local network in Knoxville, the company resolves urgent claim issues even after business hours.
They offer multi-specialty support, complete setup, and enrollment management. Known for fast results, data security, and customized billing solutions, 24/7 Medical Billing Services ensures timely support, affordable pricing, and guaranteed customer satisfaction.
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| Experience | 20 years |
8. Providers Care Billing

Providers Care Billing LLC is a leading medical billing medical billing firm Knoxville, offering comprehensive revenue cycle management for healthcare providers of all sizes and specialties. Their certified team handles billing, coding, credentialing, denial management, and accounts receivable follow-ups.
With expertise in all EHR systems, HIPAA-compliant processes, and customized solutions, they help practices improve cash flow. Providers Care Billing also employs certified coders who ensure precise ICD-10 and CPT coding.
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| Experience | 8 years |
9. MedsIT Nexus

MedsIT Nexus is another US-based medical billing company that offers services across Tennessee, including Knoxville. They offer AI-powered and cloud-based billing solutions to healthcare providers nationwide. The company ensures 99% billing accuracy and a 98.5% collection ratio.
MedsIT is trusted by 2,000+ healthcare providers across the U.S and has a 100% client satisfaction rate. They also maintains HIPAA and AAPC compliance to safeguard patient data and ensure coding precision.
| Best For | Dental, cardiology, OB-GYN, urgent care, and other specialized practices. |
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| Experience | 10 years |
10. Resilient Medical Billing Service LLC

Resilient Medical Billing Service LLC is a top-rated and affordable medical billing provider Knoxville, TN. The company provides revenue cycle management solutions to healthcare providers nationwide, including clinics, private practices, and hospitals.
They specialize in end-to-end services such as medical billing, coding, audits, provider credentialing, front office assistance, and healthcare digital marketing. Resilient MBS supports over 75 medical specialties, including family medicine, cardiology, orthopedics, and OB-GYN.
| Best For | Solo providers, multi-location practices, and large healthcare organizations |
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| Experience | 7 years |
How Our Editors Selected the Top Medical Billing Companies in Knoxville, TN?
Our editors chose the top medical billing companies in Knoxville, Tennessee, from the GBP listing and platforms like YELP, TrustPilot, and GoodFirms. Next, we carefully reviewed the companies’ websites and assessed them based on key factors.
They include HIPAA compliance, adherence to TN healthcare regulations, industry expertise, client satisfaction, and the range of RCM services offered. The companies that met these evaluation factors were chosen and were mentioned in the list of top medical billing companies in Knoxville, TN.
What are the best medical billing companies in Tennessee?
The best medical billing companies in Tennessee include Transcure, Cvikota Medical Business Services, Direct Medical Management Services Inc, and Valley View Medical Billing. These companies have decades of billing experience and offer end-to-end RCM services with accuracy and compliance with TN billing regulations.
What are the benefits of outsourcing medical billing in Knoxville, TN?
Outsourcing medical billing in Knoxville, TN, reduces administrative burden, speeds up the claim processing cycle, and minimizes coding errors. On average, outsourcing billing saves practices up to 30–40% in operational costs as compared to in-house billing.
How to choose a medical billing company in Knoxville, TN?
Choose a medical billing company in Knoxville, TN, that has expertise in your medical specialty, offers affordable pricing, and has high clean claim rates. Plus, make sure that the company offers billing services integrated within your existing EHR and provides real-time reporting features.
What percentage do medical billers take in Knoxville, TN?
Medical billers in Knoxville, TN charge approximately between 5% to 8% of total collections. However, some companies offer flexible pricing models, including per-claim charges or hourly rates, depending on the size and needs of the medical practice.
Which is the best medical billing company in Knoxville, TN?
Transcure is the best medical billing company in Knoxville. It offers AI-powered billing services along with AAPC-certified coders & billers with expertise in 40+ specialties. Moreover, they have high performance metrics, including 98% first-pass clean claim rates, 20% revenue boost , and full compliance with TN billing and payer regulations.
What are the five best medical billing companies in Knoxville, TN?
The five best medical companies in Knoxville, TN are Transcure, Cvikota Medical Business Services, Direct Medical Management Services Inc, Valley View Medical Billing, and Medisys Data Solutions Inc. These providers deliver specialty-specific billing services and have a proven success track record for Knoxville practices.
What factors should I consider before hiring a medical billing company in Knoxville, TN?
Before hiring a medical billing company in Knoxville, TN, evaluate the company’s experience, state-specific expertise, technology use, and specialty focus. Furthermore, look for HIPAA compliance, transparent pricing models, and client testimonials to ensure reliability and secure data handling.



