“The best medical billing companies in Charleston, SC, include Transcure, which helps practices streamline their billing with AI-powered agents designed for each step of the revenue cycle. Other top Charleston medical billing companies are Pettigrew Medical, EZ RCM Billing Services, LLC, and Apple Billing.”
Charleston’s healthcare industry continues to grow, and with that growth comes greater administrative complexity for local providers. Across the United States, an estimated up to 30% of healthcare revenue is lost due to claim denials and delayed payments.
As Charleston’s patient volume increases, healthcare practices face increasing pressure to manage claims accurately and speed up reimbursements. Medical billing companies in Charleston, South Carolina, help practices improve revenue cycle performance and ensure timely cash flow.
This listicle provides an expert overview of the top medical billing companies in Charleston, SC. Read on to discover which billing partners can help your practice increase reimbursements and lower administrative burdens.
- Transcure
- Pettigrew Medical
- EZ RCM Billing Services, LLC
- Apple Billing
- Superior Billing Solutions, LLC
- Medical Revenue Solutions LLC
- HMS USA
- The EMS Billing & Coding Services Of The Carolinas LLC
- 24/7 Medical Billing Services
- Lowcountry Billing Services

Table of Contents
Toggle1. Transcure

Transcure is a medical billing company in Charleston, SC that offers AI-powered billing services to healthcare practices. Our dedicated AI agents handle core RCM steps, from ELIXA, who verifies patient eligibility in 4 seconds, to DEXA, which detects, analyzes, and resolves claim denials in real time.
We also have a team of 1,100+ AAPC/AHMA-certified billers and coders, who are well-versed in 40+ specialties, including Surgery centers, Cardiology, OB GYN, and Orthopedic. This AI-powered workflow resulted in a 99.99% clean claim accuracy and maintains only a 1% claim denial rate.
Our billing team is well-versed in workflows across 40+ EHR software, including athenahealth and Epic, so practices never need to switch platforms. Transcure also provides complimentary credentialing and old AR recovery services to its clients as part of the RCM package.
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| Founded in | 2002 |
2. Pettigrew Medical

Pettigrew Medical is a leading RCM company based in South Carolina, providing medical billing and business support services to healthcare organizations across Charleston. The company was founded in 1989 by a board-certified emergency physician, with the aim of delivering technology-driven solutions to streamline billing workflows.
Its services include end-to-end revenue cycle management, clinical coding, provider credentialing, and clinical documentation improvement. Moreover, Pettigrew Medical offers staff augmentation, healthcare consulting, and custom application development.
| Best For | Healthcare provider groups, hospitals, and billing companies seeking end-to-end revenue cycle management with technology-driven solutions. |
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| Founded in | 1989 |
3. EZ RCM Billing Services, LLC

EZ RCM Billing Services, LLC is a South Carolina–based medical billing company that offers cost-efficient and HIPAA-compliant medical billing solutions. EZ RCM focuses on staying updated with payer rules, insurance updates, and regulatory changes to maximize reimbursements.
Its services include AR and denial management, eligibility verification, payment posting, charge entry, and provider credentialing. Additionally, the company is experienced with 15+ EHR systems and offers 24 – 48 Hour response times.
| Best For | Small to mid-sized healthcare practices seeking affordable and compliance-focused medical billing support. |
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| Founded in | 2018 |
4. Apple Billing

Apple Billing is a top Charleston medical billing provider, known for providing accurate and customized billing solutions for small to medium-sized healthcare practices. The company offers billing support across five specialties, including Family Medicine, Pediatrics, and Psychotherapy.
Moreover, Apple Billing ensures timely claim submissions, thorough denial management, and precise coding. They also offer proactive claim tracking, which means actively monitoring submitted claims to catch delays or issues early.
| Best For | Small to medium-sized medical practices in South Carolina looking for end-to-end RCM management. |
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| Founded in | N/A |
5. Superior Billing Solutions, LLC

Superior Billing Solutions, LLC is a U.S.-based medical billing and coding company located in South Carolina, serving the Charleston region. The company provides customized revenue cycle management, practice management, and medical credentialing services.
All services are handled in-house by U.S.-based employees, with no outsourcing to third parties. Superior Billing Solutions also provides data-driven reporting, effective communication, and personalized support through dedicated account managers.
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| Founded in | 2010 |
6. Medical Revenue Solutions LLC

Medical Revenue Solutions LLC is a Charleston medical billing agency that is part of the nation’s largest network of Medical Revenue Management offices. They specialize in practice management, revenue cycle optimization, and private practice business support.
They offer services such as iClaim for “no headache” billing, EMRx for customized workflow, QuickCollect for patient payment follow-ups, and CodeRite to maximize reimbursements. Their team provides real-time claim tracking, auditing, credentialing, and telehealth support.
| Best For | Healthcare providers of various sizes and specialties |
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| Founded in | 2011 |
7. HMS USA

HMS USA is a leading medical billing company in Charleston, South Carolina, providing accurate coding, complete claim management, and auditing services. They offer end-to-end billing, from patient registration and eligibility verification to claim submissions.
The company ensures transparency with no hidden fees and helps providers in getting credentialed with both government and private insurance companies. Furthermore, HMS USA has partnered with 500+ verified practices and claims to deliver up to 30% revenue growth.
| Best For | Multi-speciality practices, including Behavioral Health and ASC |
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| Founded in | 2019 |
8. The EMS Billing & Coding Services Of The Carolinas LLC

The EMS Billing & Coding Services Of The Carolinas is one of the best medical billing companies in Charleston, SC. The company provides comprehensive health insurance billing services, insurance authorizations, and verification services for healthcare providers across North America.
EMS Billing specializes in mental health, physical therapy, and speech therapy billing, while supporting multiple other medical specialties. In addition, they offer affordable pricing with free quotes and consultations for healthcare practices.
| Best For | Medical health care providers, including physical therapy billing, and Speech therapy billing |
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| Founded in | 2016 |
9. 24/7 Medical Billing Services

24/7 Medical Billing Services is a Charleston-based medical billing and coding company serving hospitals, clinics, and healthcare organizations across South Carolina. The company provides round-the-clock billing support, helping practices receive timely reimbursements while reducing operational costs.
Its services include end-to-end revenue cycle management, coding audits, credentialing, ICD-10 training, and medical billing consultations. With certified coding professionals and dedicated account managers, 24/7 Medical Billing Services supports multiple specialties and practice sizes.
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| Founded in | 2005 |
10. Lowcountry Billing Services

Lowcountry Billing Services is a specialized EMS billing company dedicated to supporting EMS healthcare providers across South Carolina. The company offers comprehensive EMS billing solutions, including patient billing, claims processing, regulatory assistance, and detailed revenue stream reporting.
Low Country is a trusted billing partner for 100+ EMS agencies, with more than $2 billion collected in reimbursements. Their frequent patient billing process, with statements mailed five days, helps reduce delays and maintain clear communication with patients.
| Best For | EMS agencies, including local governments, private ambulance providers, and health systems across South Carolina |
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| Founded in | 1995 |
How Our Editors Selected the Top Medical Billing Companies in Charleston, SC?
Our editors chose the top medical billing companies in Charleston, SC, from the GBP listing and platforms like YELP, TrustPilot, and GoodFirms. After that, we carefully reviewed the companies’ websites and assessed them based on key factors.
They include HIPAA compliance, adherence to SC healthcare regulations, industry expertise, client testimonials, and the range of billing services provided. The companies that met these evaluation factors were chosen and selected in our list of top medical billing companies in Charleston, SC.
What are the Best Medical Billing Companies in South Carolina?
The best billing companies in South Carolina include Transcure, Medical Revenue Solutions LLC, Medical Billing Center (MBC), EZ RCM Billing Services, LLC, and Apple Billing. These companies have decades of billing experience and offer end-to-end RCM services with accuracy and compliance with SC billing regulations.
What are the Benefits of Outsourcing Medical Billing in Charleston, SC?
Outsourcing medical billing in Charleston, SC, reduces administrative burden, speeds up the claim processing cycle, and reduces coding errors. On average, outsourcing billing saves practices up to 30–40% in operational costs as compared to in-house billing.
How to Choose a Medical Billing Company in Charleston, SC?
Choose a medical billing company in Charleston, SC, that has expertise in your medical specialty, offers affordable pricing, and has high clean claim rates. Moreover, ensure that the company provides billing support across your existing EHR and provides real-time reporting features.
What Percentage Do Medical Billers Take in Charleston, SC?
Medical billers in Charleston, SC, charge approximately between 5% to 8% of total collections. However, some companies offer flexible pricing models, including per-claim charges or hourly rates, depending on the size and needs of the medical practice.
Which is the Best Billing Company in Charleston, SC?
Transcure is the best medical billing company in Charleston, SC. The company offers AI-powered billing services along with AAPC-certified coders & billers with expertise in 40+ specialties. Moreover, they have high performance metrics, including 99.99% clean claim accuracy, 20% revenue boost, and full compliance with SC billing and payer regulations.
What are the Five Best Medical Billing Companies in Charleston, SC?
The five best medical companies in Charleston, SC are Transcure, Pettigrew Medical, EZ RCM Billing Services, LLC, Apple Billing, and Superior Billing Solutions, LLC. These billing providers deliver specialty-specific billing services and have a proven success track record for Charleston practices.
What Factors Should I Consider Before Hiring a Medical Billing Company in Charleston, SC?
Before hiring a medical billing company in Charleston, SC, review the company’s experience, state-specific expertise, technology use, and specialty focus. Moreover, confirm if the company follows HIPAA compliance, offers transparent pricing models, and has client testimonials to ensure reliability.



